Studies Closed to Enrollment


These studies are no longer active
Clinical TrialStudy Result Published
A4 Study
3-year prevention trial
AbbVie
2-year infusion study
ADMET-2
Study to treat apathy in AD
Aerobic exercise and Cognitive Training in Older Adults
ASCEND
2-year study of cardiovascular influences on AD
AVID Autopsy
A 6-mth study to evaluate new MRI techniques
Avid Autopsy
BIOGEN-FTD
1 year observational study
Calibrex
1-year study of the relationship between high blood pressure and AD
CEDAR
1-year study on the effects of candesartan vs placebo in mild cognitive impairment and Alzheimer's disease
CREAD
A 2 year infusion study to slow Alzheimer's disease (AD) progression
Atomoxetine Clinical Trial:
for people with Mild Cognitive Impairment (MCI)
Neuroimaging & Biomarkers Study - ADNI: Normal Aging, Mild Cognitive Impairment & Early Alzheimer's DiseaseOver 100 Study publications
Daybreak
A 78-week study of a drug designed to slow Alzheimer's disease (AD) progression by lowering beta amyloid production
EARLY
5-year prevention trial
EMERGE
A 12-month infusion study to slow progression of cognitive and functional impairment
Exercise and Motor Dexterity
EXERT
Study of effects of aerobic exercise on cognition
Generation 2
5 - 7 year prevention trial for healthy participants
Racial Disparities in ADL'sResults pending
Registry for Remembrance
An initiative to increase awareness & participation in neurology research
DIAN Study
2-year prevention trial
NeuroVision
2-day study that involves imaging of the retina
Right Frontal Activity in Older Adults: Does it Help or Hurt Word Retrieval?
Effects of Perceptual Interference on Memory in Mild Cognitive Impairment (MCI)
SERENE
3-month study aimed at reducing agitation and aggression in Alzheimer's disease
Tau Imaging (GN30009)
18-month observational imaging study
Tele-Savvy
A 6-week free on-line education program for informal caregivers
TRIAD
A 4-month study aimed at reducing agitation in Alzheimer's disease
VASCULAR
2-year observational study of the relationship between vascular factors and memory loss
Alzheimer's Disease Neuroimaging Initiative - GO
Pre-Mild Cognitive Impariment Study
BAN2401
A 18 month infusion study to slow Alzheimer's disease (AD) progression
EPOCH
A clinical trial testing a new treatment for Alzheimer's disease (AD)
Nerve Growth Factor: Gene Therapy Surgical Intervention TrialResults pending.
Lewy Body Disease
Cognitive Rehabilitation of Memory in Mild Cognitive Impairment
Examines changes in learning, memory, and brain activity
Cognitive Aging Project
Natural History of FTD Subtypes
Memory Training in Mild Cognitive ImpairmentResults pending
Starshine
MK8931-019
2-year trial for treatment of MCI
DHA, an Omega 3 Fatty Acide, in Slowing the Progression of Alzheimer's DiseaseDocosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trial
RAGE (Receptor for Advanced Glycation Endproducts) Inhibitor StudyPF-04494700, an Oral Inhibitor of Receptor for Advanced Glycation End Products (RAGE), in Alzheimer Disease
Caregiver Opportunities for Optimizing Lifestyles: A Research Opportunity for African American Caregivers (COOL-AD)
Development of a Biomarker for FTLD-TDP and FTLD-Tau
Cognitive Decline in Patients with Amyotrophic Lateral Sclerosis (ALS)
Agitation/Psychosis in Dementia/Parkinsonism (TAP/DAP)Quetiapine for agitation or psychosis in patients with dementia and parkinsonism.
Kurlan R, Cummings J, Raman R, Thal L for the Alzheimer's Disease Cooperative Study Group Neurology. 2007 April 24: 68; 1356-1363
Vitamins to Slow Alzheimer's Disease (Homocysteine Study) (VITAL)High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial
Mild Cognitive Impairment Study Aricept, Vitamin E or PlaceboVitamin E and donepezil for the treatment of mild cognitive impairment.
Petersen RC, Thomas RG, Grundman M, Bennett D, Doody R, Ferris S, Galasko D, Jin S, Kaye J, Levey A, Pfeiffer E, Sano M, van Dyck CH, Thal LJ; Alzheimer's Disease Cooperative Study Group, N Engl J Med. 2005 Jun 9; 352(23):2379-88. Epub 2005 Apr 13
TauRx
1 year study for treatment of bvFTD
The Role of Sleep in Cognitive Decline in Normal Aging
TOMMORROW
5-year prevention trial
VASCULAR
VASCULAR studies the role of circulatory function on memory and the risk of Alzheimer's disease.