Studies Closed to Enrollment

These studies are no longer active
Clinical TrialStudy Result Published
A4 Study
3-year prevention trial
2-year infusion study

Study to treat apathy in AD

Aerobic exercise and Cognitive Training in Older Adults

2-year study of cardiovascular influences on AD

AVID Autopsy
A 6-mth study to evaluate new MRI techniques
Avid Autopsy

1 year observational study

1-year study of the relationship between high blood pressure and AD

1-year study on the effects of candesartan vs placebo in mild cognitive impairment and Alzheimer's disease

A 2 year infusion study to slow Alzheimer's disease (AD) progression

Atomoxetine Clinical Trial:
for people with Mild Cognitive Impairment (MCI)
Neuroimaging & Biomarkers Study - ADNI: Normal Aging, Mild Cognitive Impairment & Early Alzheimer's Disease

Over 100 Study publications

A 78-week study of a drug designed to slow Alzheimer's disease (AD) progression by lowering beta amyloid production

5-year prevention trial

A 12-month infusion study to slow progression of cognitive and functional impairment

Exercise and Motor Dexterity

Study of effects of aerobic exercise on cognition

Generation 2
5 - 7 year prevention trial for healthy participants
Racial Disparities in ADL's

Results pending

Registry for Remembrance
An initiative to increase awareness & participation in neurology research

DIAN Study
2-year prevention trial

2-day study that involves imaging of the retina

Right Frontal Activity in Older Adults: Does it Help or Hurt Word Retrieval?

Effects of Perceptual Interference on Memory in Mild Cognitive Impairment (MCI)

3-month study aimed at reducing agitation and aggression in Alzheimer's disease

Tau Imaging (GN30009)
18-month observational imaging study

A 6-week free on-line education program for informal caregivers

A 4-month study aimed at reducing agitation in Alzheimer's disease

2-year observational study of the relationship between vascular factors and memory loss

Alzheimer's Disease Neuroimaging Initiative - GO
Pre-Mild Cognitive Impariment Study

A 18 month infusion study to slow Alzheimer's disease (AD) progression

A clinical trial testing a new treatment for Alzheimer's disease (AD)

Nerve Growth Factor: Gene Therapy Surgical Intervention Trial

Results pending.

Lewy Body Disease

Cognitive Rehabilitation of Memory in Mild Cognitive Impairment
Examines changes in learning, memory, and brain activity

Cognitive Aging Project

Natural History of FTD Subtypes

Memory Training in Mild Cognitive Impairment

Results pending


2-year trial for treatment of MCI

DHA, an Omega 3 Fatty Acide, in Slowing the Progression of Alzheimer's DiseaseDocosahexaenoic acid supplementation and cognitive decline in Alzheimer disease: a randomized trial

RAGE (Receptor for Advanced Glycation Endproducts) Inhibitor StudyPF-04494700, an Oral Inhibitor of Receptor for Advanced Glycation End Products (RAGE), in Alzheimer Disease

Caregiver Opportunities for Optimizing Lifestyles: A Research Opportunity for African American Caregivers (COOL-AD)

Development of a Biomarker for FTLD-TDP and FTLD-Tau

Cognitive Decline in Patients with Amyotrophic Lateral Sclerosis (ALS)

Agitation/Psychosis in Dementia/Parkinsonism (TAP/DAP)Quetiapine for agitation or psychosis in patients with dementia and parkinsonism.
Kurlan R, Cummings J, Raman R, Thal L for the Alzheimer's Disease Cooperative Study Group Neurology. 2007 April 24: 68; 1356-1363

Vitamins to Slow Alzheimer's Disease (Homocysteine Study) (VITAL)High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial

Mild Cognitive Impairment Study Aricept, Vitamin E or PlaceboVitamin E and donepezil for the treatment of mild cognitive impairment.
Petersen RC, Thomas RG, Grundman M, Bennett D, Doody R, Ferris S, Galasko D, Jin S, Kaye J, Levey A, Pfeiffer E, Sano M, van Dyck CH, Thal LJ; Alzheimer's Disease Cooperative Study Group, N Engl J Med. 2005 Jun 9; 352(23):2379-88. Epub 2005 Apr 13

1 year study for treatment of bvFTD

The Role of Sleep in Cognitive Decline in Normal Aging

5-year prevention trial

VASCULAR studies the role of circulatory function on memory and the risk of Alzheimer's disease.