According to the National Institutes of Health (NIH) there is no definitive evidence yet about what can prevent Alzheimer’s or age-related cognitive decline. What we do know is that a healthy lifestyle—one that includes a healthy diet, physical activity, appropriate weight, and no smoking—can maintain and improve overall health and well-being. The NIH believes making healthy choices can also lower the risk of certain chronic diseases, like heart disease and diabetes, and scientists are very interested in the possibility that a healthy lifestyle might have a beneficial effect on Alzheimer’s as well. Our scientists are focused not only on identifying the causes of Alzheimer’s disease but determining what novel approaches can prevent Alzheimer’s disease. In the meantime, as research continues to pinpoint what works to prevent Alzheimer’s, people of all ages can benefit from taking positive steps to get and stay healthy.